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I'm a third year medical student and given my affinity with electronic music, background in drumming and predilection for cardiology, I was inspired to mix heart sounds and murmurs with some house tracks. I figure if you can distinguish heart sounds amongst other beats, you can hear them in people.
The heart sound during the first half of the "house is where the heart is" mix is a mid systolic click (associated with mitral valve prolapse), followed by a fixed split S2 (associated with atrial septal defect) starting around 2:40. I blame any poor beat matching on sinus arrhythmia! Here are brief medical explanations of the heart sounds:
Mid Systolic Click (at 128 beats per minute):
Prolapse of the mitral valve is heard as a "click" between S1 and S2. Immediately after the click, a crescendo-decrescendo murmur can be heard at the apex. Mitral valve prolapse is enhanced by Valsalva maneuver or standing (decreased venous return so prolapse occurs earlier) and decreased by squatting (increased venous return and chordae tendineae tension). Depending upon the amount of venous return, the intensity of the murmur may vary.
Fixed Split S2 (at 63 beats per minute):
A "fixed" split S2 heart sound is the most characteristic feature of an atrial septal defect (left to right shunt). This is in contrast to transient split S2 caused physiologically during respiration in people without ASD due to increased venous return to the right ventricle and delayed closure of the pulmonary valve in relation to closure of the aortic valve. In ASD, the right ventricle is consistently full because of the pressure gradient, producing a split S2. Furthermore, inspiration produces no net pressure change between the atria in ASD, so S2 does not vary from inspiration to expiration (i.e. fixed).
Reference: The Auscultation Assistant http://www.wilkes.med.ucla.edu/inex.htm.
Tracks: Central Park by Karim Shaker and La Pierre Pilie by Roch Dadier.
Special thanks to Visual Communication Services at Texas Heart Institute for permission to use the heart sounds in this project.
Stay tuned for a new heart mix featuring S3, loop diuretics, Bulgarian vocals, and perhaps telemetry visuals!
"Von Gierke's robot" is a mash-up I did last year between Daft Punk's Robot Rock and my colleague SubstanceP's glycogen storage disease medley from the USMLE Study Songs series. Hear the original at http://www.youtube.com/watch?v=1J5EZoDx5FA&feature=channel_page.
Software: Audacity.
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