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In 1995 they released their first demotape "Dark hearth behind" raw old style but melodic thrash-death influenced by Slayer , Morbid Angel ecc.

After some gigs Disease started to write new material and in the summer of 1996 they released their second work , a promo of two songs that was enthusiastically rated by magazines , fanzines and metal fans. After other problems with members and new line-up changes , the band started to insert new music influences out from the tradicional way of death-thrash . New prog and melodic part were added , mixed with extreme metal and techinical parts : riff work became more complex, the voice alternated clean parts to growls giving to Disease a new musical identity which actually characterizes the group.

During september 1997 Marco Mastruzzi (guitar) entered in the band . In the summer of 1998 Disease released "ADVTIXVIII" that changed definitely their musical prospective trying to destroyed all the barriers of genres : mixing extreme metal parts with melodies and progressive arrangments .

In the 1999 new important line-up changes transformed the face of the band : Leonardo Orazi became the new bassist and after a long search to find a good vocalist in 2001 Flavio decided to take the role playing guitar and singing at the same time .

After a lot of lives and a home-demo never released (recorded in the october 2001) the band started to compose the new material for their first album "5th wave , endless".

In 2004 Disease released "Burning memories - demo coll. 1995-2001" a retrospective for their 10 years anniversary of activity in the metal underground :the cd compilation that includes all the demos of the band raised a good feedback in the underground and helped the band to join Deadbang record that produced their first album "5th wave , endless" , released in May 2005 : The debut album was more complex and complete than the old released material for a perfect integration of extreme metal fury , melodic , progressive parts and a multicolour voice between extreme screams/growls and melodic clean vocals .

The band started to support the album with shows : they played with some italian underground band and in the spring od 2006 was the opening act of the gig of Sadus & Darkane in Rome .

In the summer of 2006 the band played at the Mostra dei Mostri fest in Cellino Attanasio (with Extrema , Infernal Poetry , ecc) where they recorded their performance released in the 2007 as a free bootleg , you can find it on www.diseasemetal.it on the download sez. .

In the spring of 2008 the band re-recorded 3 old songs from their 1998 “ADVTIXVIII” re-arranged in the way of their actual musical direction : with the supervision of Joseph DiPorto on the mixer , the band recorded the 3 track absolutley live trying to combine all music in a unique suite of 32 minutes full of some different atmospheres and contrasts . The result of the hard work ( infinite thanks to the patience and to the talent of our brother Joseph) is called “A circular decade in motion “ and will be release in september / october 2008 . Now the band is at work to ultimate the composition of their new album , 5 songs are ready and some new stuff is coming out ... Wait for new etreme – progressive tunes , Disease will return really soon !!

1995 Dark heart behind (demo)

1996 Promo 1996

1997 Screams from italy vol.3 (cd compilation out for Dawn of sadness rec.)

1998 ADVTIXVIII (5 songs promo)

2001 Promo 2001 (never released )

2005 5TH WAVE , ENDLESS (debut album on Deadbang rec.)

2007 Live bootleg

2008 A circular decade in motion .